Plot of the movie centred around a young (newlywed?) couple on a road trip across America who get harassed by malicious eccentrics (who are possibly demons?) on the way, until eventually they get separated with the woman getting abducted by some nut job in a car (and taken to hell?), leaving the man struggling to give chase, overcoming various encounters and obstacles in order to find her and win her back.
Highway to Hell (1992)?