Desert roadtrip movie (?)

In the early 90s I saw a film at a friends house.  I dont really remember the plot but I think it took place in the american southwest and involved a road trip.  I have a feeling the film was made in the late 70s or the 80s.  I vaguely remember a man, or possibly two men, travelling in a station wagon or other large car with a blonde.  At one point there is a  scene where the girl is holding a gun at the guys head and I remember her makeup being dark and heavy especially around the eyes.  I think drugs were involved.  At another point I think they stopped by a lake or waterfall.  Anyone have any ideas.  I dont think I can provide any more details.  Just wanted to throw this our there.  I appreciate any responses.  Thank you.

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